Self-Reporting Fluorescent Prodrug for Esterase-Guided Drug Release and Inflammation-Triggered Bioimaging
Stimuli-responsive prodrugs that combine therapeutic efficacy with optical reporting offer promising avenues for precision medicine. This study presents a dicyanoisophorone−naproxen (DCIP−Nap) conjugate, which merges the anti-inflammatory effects of naproxen with a donor−π−acceptor fluorescent scaffold. Initially, th...