Author

A. Abi-Dargham

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Review Jul 2026

Toward a Pluralistic Model for the Schizophrenia Spectrum-Dopamine and Beyond.

Dopaminergic hyperactivity may be a key mechanism for core psychotic symptoms in many patients, but it is unlikely that dopamine dysregulation is a universal final common pathway across symptom domains.

M. Keshavan, Henry A. Nasrallah, A. Abi-Dargham et al. · JAMA psychiatry · 0 citations