Open access
Aug 2026
Hydrogels and nanogels based on 2Nap-capped cationic tripeptides: influence of lysine position and siRNA delivery properties.
The delivery of therapeutic short interfering RNA (siRNA) is hindered by biological barriers such as rapid degradation and poor cellular uptake. This study investigates peptide-based nanogels (NGs) as potential delivery platforms using three N-capped tripeptides, 2NapKFF, 2NapFKF, and 2NapFFK, designed to load siRNA vi...
Mariangela Rosa, Fin Hallam Stewart, C. Diaferia et al.
· Biomaterials Science · 0 citations