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Review Open access Sep 2026

Catheter Ablation Versus Medical Therapy in Atrial Fibrillation With Heart Failure With Reduced or Mildly Reduced Ejection Fraction: A GRADE‐Assessed Systematic Review and Meta‐Analysis

ABSTRACT Background Catheter ablation is an established rhythm‐control strategy for atrial fibrillation (AF), but its effectiveness in patients with heart failure with reduced or mildly reduced ejection fraction (HFrEF/HFmrEF) remains incompletely defined. We performed a GRADE‐assessed systematic review and meta‐analys...

A. A. Malik, Nasir Saeed, Goodluck Oparaugo et al. · 0 citations
Review Open access Sep 2026

Efficacy and safety of daratumumab-based quadruplet therapy vs non-daratumumab-based triplet therapy in newly diagnosed multiple myeloma patients: A GRADE assessed systematic review and meta-analysis of randomized controlled trials

Background Multiple myeloma (MM) is the second most common hematologic malignancy worldwide. Recent therapeutic innovations, including the addition of daratumumab to standard regimens, have shown promising improvements in patient outcomes. Objectives This study aims to compare the efficacy and safety of daratumumab-bas...

M. Osama, Muhammad Haris Khan, Ammara Tahir et al. · 0 citations

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