Author

A. Aguglia

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Sep 2026

Clinical Predictors of Lithium Response in Patients with Bipolar Disorder: Potential Predictive Role of Chronotype, Rumination and Traumatic Events.

INTRODUCTION Bipolar Disorders (BD) are severe, recurrent, and well-characterized psychiatric conditions with lithium as the first-line approved treatment for BD. This study aims to evaluate lithium response using the ALDA scale and to identify reliable predictors in a cohort of patients with BD. METHODS In this cros...

A. Aguglia, G. Breda, Valentina Aprile et al. · Current Neuropharmacology · 0 citations

Open access Sep 2026

Predicting early psychiatric readmission among people with major depressive disorder: A machine learning analysis from the prospective multicentre DEEP READ study.

These findings suggest that standard clinical variables may hold predictive value for early readmission in MDD, however, external validation, assessment of model calibration, and clinical utility are needed prior to clinical implementation.

F. Bartoli, M. Luciano, C. Crocamo et al. · Journal of Affective Disorde... · 0 citations

Open access Aug 2026

Differential associations of inflammatory-metabolic markers with depressive symptom dimensions: Towards a clinical phenotyping of immune-metabolic depression.

BACKGROUND Depression is increasingly conceptualized as a biologically heterogeneous condition, with immune-inflammatory and metabolic dysregulation implicated in specific symptom dimensions rather than overall depressive severity. However, it remains unclear whether different combinations of inflammatory and metabolic...

M. Di Nicola, M. Pepe, A. Aguglia et al. · Psychoneuroendocrinology · 0 citations