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Open access Aug 2026

Drug Repurposing of Verapamil for Radiation-Induced Enteropathy: Regulation of 5-LOX, Nrf2, and Intestinal Barrier Function

Aim: Radiation-induced intestinal injury is one of the major dose-limiting complications of abdominal radiotherapy and is closely associated with oxidative stress, inflammation, and disruption of epithelial barrier integrity. The present study aimed to investigate the protective effects of verapamil on radiation-induce...

M. Daşıran, Hassen Daghmoura, A. Akbaş et al. · 0 citations
Open access Aug 2026

Predictive Value of Histopathological Variables and Peripheral Immune-Inflammatory Markers in De Novo Metastatic Breast Cancer: Development and Clinical Utility of the Novel KiTNASP Score

Background and Aim: Approximately 10% of breast cancer patients present with distant organ metastases at initial diagnosis. This study aimed to evaluate the efficacy of immune-inflammatory markers and histopathological variables in identifying de novo metastatic breast cancer. Methods: Patients with breast cancer refer...

Serkan Yılmaz, M. Yur, E. Aygen et al. · 0 citations

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