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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

A. Al Tuwaijri

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4 papers indexed here

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Open access Oct 2026

Inhibition of Monoacylglycerol Lipase Suppresses Lipopolysaccharide-Enhanced Melanoma Proliferation and Migration

Background/Objectives: Lipid metabolism dysregulation contributes to cancer progression. Monoacylglycerol lipase (MAGL) breaks down 2-arachidonoylglycerol (2-AG) into glycerol and arachidonic acid, a substrate for cyclooxygenase-2 (COX-2) to produce pro-inflammatory mediators such as prostaglandin E2 (PGE2). Lipopolysa...

Faris Almutairi, Yazeed Alneef, H. Albassam et al. · 0 citations
Open access Sep 2026

Low Molecular Weight Dextran Sulfate Mitigates Acute Kidney Injury Induced by Renal Ischemia/Reperfusion: Implication of JNK/p38 MAPK and Caspase-3

Renal ischemia/reperfusion injury (RI/RI) is one of the major causes of acute kidney injury (AKI). Low molecular weight-dextran sulphate (LMW-DS) is a bioactive polysaccharide with anti-inflammatory and cytoprotective properties. This study investigated the nephroprotective potential of LMW-DS against the RI/RI. RI/RI...

Nadrah S. Alamri, Ahlam M. Alhusaini, W. Sarawi et al. · 0 citations
Open access Sep 2026

Impact of Cannabidiol and Its Synthetic Derivative on Fentanyl Consumption and Fentanyl-Induced Neurometabolic Alterations in Mice

Background: Opioid use disorder (OUD) remains a critical global health challenge, with highly potent synthetic opioids like fentanyl contributing to overdose deaths. The available treatments have limitations. The endocannabinoid system has emerged steadily as a therapeutic target for the opioid crisis due to its modula...

Dalal A. Alkhelb, Jomana M. Alahmadi, Maisa S. Alqarni et al. · 0 citations
Open access Jul 2026

Involvement of NOD1/NF-κB/MAPK pathway in the protective effect of procyanidin B2 against methotrexate-induced nephrotoxicity

Objective Methotrexate (MTX) is a very effective agent used to treat rheumatoid arthritis and malignant diseases. Despite its usefulness, the long-term use of MTX is associated with multiorgan toxicities, including kidney injury. Thus, there is a necessity to explore a renoprotective agent with low side effects. Procya...

A. Al Tuwaijri, Ahlam M. Alhusaini, W. Sarawi et al. · 0 citations

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