A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering
The success of inhaled mRNA therapeutics remains limited by the absence of aerosol optimized ionizable lipids and incomplete understanding of formulation device interactions. Here we present an integrated platform for pulmonary mRNA delivery combining novel lipid chemistry, systematic formulation engineering, and d...