This review provides an integrated overview of the molecular and genetic determinants governing biofilm development, including surface attachment, matrix biosynthesis, quorum-sensing networks, cyclic-di-GMP signaling, maturation, and dispersal.
T. Chakraborty, Madhuchhanda Chatterjee, Sayanika Das et al.· Infection, Genetics and Evol...· 0 citations
Structural insight is offered of dacB variants leading to antibiotic resistance and the need to prioritize specific antibiotics to address the challenges arising from protein mutations is emphasized.
Shalini Mathpal, Maruthan Karthik, T. Joshi et al.· Scientific Reports· 0 citations
This review was developed following a structured literature search of major biomedical databases and clinical trial registries to synthesize current evidence on the therapeutic applications of CRISPR-Cas9 in oncology and inherited genetic disorders.
Khushi Bashir, Prathiksha Vasudev, Vikas Chhetri et al.· Frontiers in Genome Editing· 0 citations
This review underscores the critical role of bioinformatics in addressing the global burden of MDR-TB and highlights its transformative role in guiding next-generation anti-TB drug development.
Elizabeth Annie George, Mahima Senthilkumar, Kavitha Thirupugazh et al.· Beni-Suef University Journal...· 0 citations
Canagliflozin is suggested as a potent PBP3‐binding drug against the A. baumannii pathogen, which stands as a critical priority pathogen, rapidly developing resistance against the currently available antibiotic treatments, including last‐resort antibiotics.
Srujal Kacha, A. Anbarasu· ChemistrySelect· 0 citations
The findings underscore the complex interplay between ARGs, VFs, and MGEs in the genomic evolution of CRAB, expanding current understanding of CRAB adaptation and may contribute toward enhanced surveillance, antimicrobial stewardship, and exploration of alternative therapeutic targets.
Sara Pearl, A. Anbarasu· Frontiers in Cellular and In...· 0 citations
The role of multimodal artificial intelligence and machine learning in bridging the gap in interpreting heterogeneous modalities to improve risk prediction, prognostic assessment, and treatment decision-making in precision oncology is focused on.
Shruthi Suresh, A. Parvathy, Megha Raj et al.· Frontiers in Digital Health· 0 citations
Vc7 has been identified as a structurally stable and highly immunogenic construct, suggesting its potential as a universal multi-epitope vaccine candidate for the prevention of brucellosis.
Rhitam Biswas, Swapno Surabhi Sinha, Aditi Roy et al.· Frontiers in Bioinformatics· 0 citations
This review aims to assess how AI- and ML-driven multi-omics offer comprehensive insights into pathogenicity, thereby enhancing diagnostic techniques and personalized therapeutic approaches in Crohn's disease and enhancing precision healthcare delivery.
