Open access
Jul 2026
Integrated meta-analysis of human astrocytes transcriptomes reveals a candidate recurrent inflammatory signature in response to inflammatory and immune stimuli
The consistent upregulation of DDX58 and IFIH1 across varied inflammatory stimuli suggests that astrocytes transition into a common ‘reactive’ state that may contribute to chronic neuroinflammation, underscores the dual protective and pathological roles of astrocytes in inflammatory processes.
Andrea Luque-Bolivar, Karem Ruiz-Araujo, A. Aristizábal-Pachón et al.
· Frontiers in Cellular Neuros... · 0 citations