Open access
Sep 2026
Metformin Attenuates Behavioral Deficits and Oxidative Stress in a Preclinical Model of Autism
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental condition lacking effective pharmacological treatments. Metformin has emerged as a candidate for drug repurposing in ASD due to its metabolic and neurobiological actions. This study evaluated the in vivo effects of metformin (400 mg/kg, orally) adm...
Madna Costa Freitas, Renê Felipe de Freitas, Iara Késsila Milhome Vasconcelos et al.
· Developmental Neurobiology · 0 citations