Author

A. Bernhardt

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Open access Sep 2026

Longitudinal Dynamics of the Blood Proteome Within the Alzheimer Spectrum in Down Syndrome

Background and Objectives Adults with Down syndrome (DS) have an increased risk of developing early Alzheimer disease. While our previous cross-sectional study investigated the blood proteome in the context of Alzheimer in DS, identifying CBLN4, CD14, C-X-C motif chemokine 17 (CXCL17), ectodysplasin A2 receptor (EDA2R)...

Olivia Wagemann, Georg S. Nuebling, K. Sandkühler et al. · Neurology · 0 citations

Open access Sep 2026

Dynamic [18F]PI-2620 recording facilitates prediction of β-amyloid positivity and simultaneous staging of tau and neurodegeneration

Dynamic [18F]PI-2620 PET imaging facilitates assessment of the β-amyloid status and regional staging of tau and neurodegeneration during a single acquisition, and may reduce radiation exposure, streamline diagnostic workflows, and facilitate personalized disease profiling.

Johannes S. Gnörich, J. Kusche-Palenga, Agnes Kling et al. · Molecular Neurodegeneration · 0 citations

Aug 2026

[Multiple system atrophy].

Ongoing research aims to establish sensitive biomarkers, identify prodromal disease stages, and develop targeted interventions addressing key pathophysiological mechanisms such as α-synuclein aggregation and neuroinflammation.

I. Wilkens, Sabrina Katzdobler, A. Bernhardt et al. · Fortschritte der Neurologie... · 1 citation