1,3‐Dipolar Cycloaddition of Nitroalkanes as a Tool of DOS/LOS‐Like Strategy for the Synthesis of Isoxazoles and Isoxazolines
An efficient and common strategy for the generation of pharmaceutically relevant functionalized molecules based on the diversity‐ and lead‐oriented synthesis (DOS/LOS)‐like concepts is presented. The approach is implemented for the case of functionalized sp3‐enriched derivatives of isoxazole and isoxazoline. The key ch...