A. Bharat

Pathological Th2 cell activation via STAT6 pathway for pulmonary fibrosis.

Coronary Calcium Screening and Incidental Lung Cancer Detection in Patients Ineligible for US Preventive Services Task Force Screening.

BACKGROUND Current US Preventive Services Task Force lung cancer screening criteria exclude an estimated 40%-70% of individuals who ultimately develop lung cancer. Coronary calcium screening CT routinely captures thoracic anatomy and may provide an opportunity for earlier lung cancer detection outside established scree...

Hypercapnia enhances airway smooth muscle contractility via STIM1-dependent Ca2+ signaling.

Hypercapnia, elevated carbon dioxide (CO2), is common in advanced chronic obstructive pulmonary disease (COPD) and predicts poor clinical outcomes. Traditionally considered a consequence of disease severity, hypercapnia may drive disease progression by promoting airway dysfunction. Here, we show that hypercapnia acts a...