Development And Optimization Of Baicalin Nanoparticle Loaded Oral Hydrogel For Colon-Targeted Therapy In Inflammatory Bowel Disease
The developed nanoparticle-loaded oral hydrogel offers pH-responsive colon targeting, strong mucoadhesion, and sustained drug release, presenting significant clinical potential for localized IBD therapy with reduced systemic toxicity and improved patient compliance, warranting further in vivo validation.