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Author

A. Bonnefond

2 papers indexed here

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Aug 2026

Immunometabolic endotypes define distinct clinical trajectories in type 2 diabetes.

Type 2 diabetes (T2D) is a heterogeneous disease, yet current classifications do not capture its clinico-biological complexity or support precision-based care. We developed an endotyping strategy based on routine blood immune cell counts across more than 1,500 individuals with newly diagnosed T2D from three European co...

B. Vuong, Chloe Delepine, Jacqueline M. Ratter-Rieck et al. · 0 citations
Open access Aug 2026

Hepatic stellate cell FXR signaling regulates context-dependent functions in liver homeostasis and fibrosis

Nuclear bile acid (BA) signaling plays a central role in liver homeostasis and represents a major therapeutic axis in fibrotic liver diseases. The farnesoid X receptor (FXR), a master nuclear effector of BA signaling, is expressed in several liver-resident cell types, suggesting that it may regulate distinct biological...

Manjula Vinod, F. P. Zummo, Céline Gheeraert et al. · 0 citations

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