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Open access Oct 2026

Acute Enlargement of a Frontal Calvarial Lesion in Polyostotic Fibrous Dysplasia Associated with McCune-Albright Syndrome: A Case Report

Background: McCune–Albright syndrome (MAS) is a rare mosaic disorder caused by postzygotic activating mutations in GNAS, classically presenting with fibrous dysplasia (FD), hyperpigmented macules, and endocrinopathies. Craniofacial FD is common and typically follows a benign course. However, acute symptomatic changes w...

David Zhang, Rachel Multz, P. Jamshidi et al. · 0 citations
Aug 2026

Lesion Expansion in Craniofacial Fibrous Dysplasia: Natural History and Indicators of Progression in the Frontal, Zygomatic, and Sphenoid Bones.

Fibrous dysplasia (FD) is characterized by expansile fibro-osseous lesions that may occur in association with endocrinopathies as part of McCune-Albright syndrome (MAS). Craniofacial FD may result in substantial morbidity, including facial asymmetry and compression of vital neurovascular structures. There is a critical...

J. Freeman, Ibrahim I. Elbashir, Kristen S. Pan et al. · 0 citations

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