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Open access Aug 2026

Assessment of the choroid plexuses volume in radiologically isolated syndrome

Objective: to investigate the volume of the choroid plexuses (ChP) in individuals with radiologically isolated syndrome (RIS) and its impact on conversion to multiple sclerosis (MS), and to assess the level of neuroinflammation in individuals with RIS. Material and methods. A prospective observational study wa...

D. V. Kapkanets, A. Boyko, M. B. Dolgushin et al. · 0 citations
Open access Aug 2026

Clinical and immunological markers of transformation of an acute demyelinating episode to a chronic demyelinating disease

An acute demyelinating episode (ADE) is the acute onset of clinical symptoms characteristic of multiple sclerosis (MS) or other demyelinating diseases (DD). Patients with ADE may experience either a monophasic course of the disease, relapses, or transformation to MS (up to 33 per cent). To date, there are no criteria f...

G. I. Sadekova, V. Millan Grishina, M. Kozin et al. · 0 citations
Open access Aug 2026

The search for polyphenolic inhibitors of BTK (Bruton’s tyrosine kinase) for the treatment of multiple sclerosis using machine learning methods

Objective: development of a machine learning model to predict the inhibitory activity of natural compounds, predominantly of a polyphenolic nature, against Bruton’s tyrosine kinase (BTK), with the aim of identifying potential candidates for the treatment of multiple sclerosis (MS) with a favourable safety profile....

V. Rogovskii, A. Kukushkina, A. Boyko · 0 citations

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