Nicotinamide adenine dinucleotide (NAD) occupies a privileged position at the intersection of cellular bioenergetics, redox homeostasis, and signal transduction. Beyond its canonical role in ATP synthesis, NAD serves as an obligate cofactor for enzymes including poly(ADP-ribose) polymerases (PARPs), sirtuins, and CD38,...
Leire Arrizabalaga, Laura Santambrogio, G. Kroemer et al.· Cell Metabolism· 0 citations
Analysis of transcriptional signatures of immune cell infiltration across three public transcriptomic datasets from patients with breast cancer suggests interactions between mast cells and non-malignant components of the breast cancer microenvironment, particularly fibroblasts, may shape disease progression and treatme...
A. Kirchmair, C. Galassi, E. García-Torralba et al.· Genes and Immunity· 0 citations
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