Repair-associated epigenetic memory: A conceptual framework for persistent chromatin signatures following DNA double-Strand break repair.
DNA double-strand breaks (DSBs) represent one of the most deleterious forms of genomic damage and are repaired primarily through non-homologous end joining (NHEJ) and homologous recombination (HR). Although these pathways efficiently restore DNA sequence integrity, increasing evidence indicates that DNA repair is accom...