Author

A. C. Ha

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Open access Sep 2026

pH-Responsive Freeze-Thawed Polyvinyl Alcohol/Chitosan Hydrogels for Topical Delivery of Anti-Inflammatory, Antioxidant, and Antibacterial Piper betle Leaf Extract Toward Wound Healing Applications

Piper betle leaf extract (BLE) shows strong anti-inflammatory, antioxidant, and antibacterial activities. However, its application is limited due to poor water solubility, oxidative instability, and rapid clearance from the application site. To address these challenges, a crosslinker-free polyvinyl alcohol/chitosan (PV...

N. H. Do, Ha Vu Le, K. D. Nguyen et al. · Indonesian Journal of Chemis... · 0 citations

Sep 2026

Response surface optimization of thermosensitive chitosan-polyvinyl alcohol hybrid hydrogels with enhanced betel leaf extract release for localized anti-inflammatory therapy.

The optimized hybrid hydrogel is established as a bio-functional, thermo-responsive network capable of coupling elasticity with bioactive extract release behavior, offering a promising candidate towards localized anti-inflammatory therapy.

N. H. Do, Mai Thi Phuong Nguyen, A. C. Ha · Soft Matter · 0 citations