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A. C. Munoz

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Review Open access Oct 2026

Dose-related effects of olezarsen in hypertriglyceridaemia: a systematic review and meta-analysis of 2,610 patients

Hypertriglyceridaemia is characterised by accumulation of triglyceride-rich lipoproteins (TRLs) contributing to residual atherosclerotic cardiovascular risk. Olezarsen is a GalNAc-conjugated antisense oligonucleotide targeting hepatic ApoC-III mRNA, thereby lowering ApoC-III and accelerating TRL clearance. We per...

A. C. Fernandez, S. M. Topete, M. Mejia et al. · 0 citations

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