Open access
Sep 2026
Hierarchical and context-dependent GR-MR signalling governs endogenous corticosteroid decoding in the heart
It is shown that corticosteroid responses are governed by a functional GR-MR hierarchy and by cellular context, which identifies hierarchical and context-dependent GR-MR signalling as a mechanism of corticosteroid decoding and a potential route to cardiac regeneration.
F. Sacchi, S. Boriati, R. Caliandro et al.
· bioRxiv · 0 citations