NeuroImage: Clinical
N. Molchanova, A. Cagol, M. Ocampo-Pineda et al.
· 212 citations
· ⚡13
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Open access
Aug 2026
Central vein sign and paramagnetic rim lesions in pediatric-onset multiple sclerosis: a systematic review and meta-analysis
Susceptibility-based MRI biomarkers, including paramagnetic rim lesions (PRLs) and central vein sign (CVS), were incorporated into the 2024 McDonald criteria because they improve diagnostic specificity in adult-onset MS; however, their role in pediatric-onset MS (POMS) remains incompletely defined. To synthesize curren...
Anna de Mauro, Rosa Cortese, Giulia Fadda et al.
· Journal of Neurology · 0 citations
Open access
Aug 2026
Serum Glial Fibrillary Acidic Protein Dynamics, Disease Progression, and Therapy Response in Multiple Sclerosis.
It is suggested that serum GFAP may serve as a biomarker for personalized risk stratification and treatment monitoring and as a screening tool to reduce cohort size in clinical trials targeting MS progression.
M. Einsiedler, S. Sandgren, S. Schaedelin et al.
· JAMA Neurology · 0 citations
Jul 2026
Choroid plexus morphological and microstructural changes across inflammatory phenotypes in multiple sclerosis.
CP volume was increased in both active RMS and inactive PMS and was associated with lower total and cortical brain volumes, suggesting CP volume may reflect processes beyond MS-specific pathology, including physiological factors.
M. Mastantuono, A. Cagol, M. Ocampo-Pineda et al.
· Multiple Sclerosis · 0 citations