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Author

A. Carbone

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Open access Jul 2026

X-PAIR: an ultrafast multitask framework for proteome-scale reconstruction of PPI networks and partner-specific interfaces from sequence

X-PAIR is presented, a sequence-based multitask deep learning framework that jointly predicts whether two proteins interact and identifies their partner-specific interface residues, and links proteome-scale interaction discovery to the residue-level determinants of partner-specific molecular recognition.

S. Rescalli, A. Carbone · 0 citations
Open access Aug 2026

PLMView: collaborative protein language model representations for fast and scalable specialized protein function inference

Applications to thioredoxins, visual opsins, and Tara Oceans environmental diatom cold-shock proteins show that PLMView can move from interpretable residue-level determinants in well-studied protein families to large-scale environmental functional discovery, linking molecular specialization to ecological distribution and transcriptional deployment across the global ocean.

Vinh-Son Pho, Alessandro Natale Bianchi, Mattéo Scarsini et al. · 0 citations