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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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A. Carugo

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Jul 2026

Abstract A027: Leveraging genomic copy-number complexity in uveal melanoma to drive novel therapeutic development

Uveal Melanoma (UM) is a rare tumor characterized by activating mutations in GNAQ or GNA11, followed by a secondary mutation in BAP1, SF3B1 or EIF1AX. Notably, chromosome 3 copy-number loss, enriched among BAP1-mutant patients, is associated with an increased likelihood of metastasis. While chromosome 3 loss remains...

Johnathon L. Rose, Sanjana Srinivasan, A. Cooper et al. · 0 citations

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