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Open access Jul 2026

C3 complement inhibition by Sicpin, a salivary protein from Simulium nigrimanum 2328025

Complement inhibition is a key strategy used by many blood-feeding arthropods to ensure successful feeding. Mosquitoes, ticks, sand flies, and other hematophagous species secrete salivary proteins that block different steps of the complement cascade. These inhibitors prevent complement-mediated lysis and inflamma...

Paola Carolina Valenzuela Leon, Molly Ring, Brian Bonilla et al. · 0 citations

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