Open access
Jul 2026
Cross-species variant-to-function analyses implicate MEIS1 in conferring sleep abnormalities and impaired cerebellar development.
Zebrafish is established as an efficient vertebrate platform for functional interrogation of GWAS candidates and an evolutionarily conserved cerebellar role for MEIS1 in sleep maintenance is supported, indicating conserved regulatory architecture spanning the human insomnia-associated locus.
A. Zimmerman, Erika Almeraya Del Valle, M. Pahl et al.
· Genome Research · 0 citations