Monoclonal antibodies (mAbs) that target receptor-mediated oncogenic pathways have revolutionized oncology research. Better therapeutic indices are possible with these mAbs for targeted tumor treatment. This review covers receptor-targeted monoclonal antibodies targeting the EGFR, HER2, and VEGF pathways in solid t...
A. Chettupalli, Paramvir Singh Tomar, Shikha Yadav et al.· Current Drug Therapy· 0 citations
Medicinal plants provide an important source of structurally varied bioactive metabolites with medicinal potential; however, their effective extraction, characterization, and standardization present considerable analytical challenges. Counter-current separation (CCS) methods, such as centrifugal partition chromatograph...
A. Chettupalli, Priyanshu Pathak, Priya Sharma et al.· Frontiers in Pharmacology· 0 citations
Very precise and individualized approaches developed in chemotherapy have dramatically transformed the treatment of cancer using non-selective cytotoxic agents. In the field of molecular biology, these breakthroughs enabled the development of targeted medications that selectively block the activation of oncogenic p...
S. Rahaman, Sakshi Patel, Rahul Kumar et al.· Current Drug Therapy· 0 citations
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