Author

A. D. da Silva

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Review Open access Aug 2026

Parental Obesity and Offspring Risk for Cardiorenal Diseases

Obesity rates have increased dramatically during the past four decades, and these increases have occurred in children and adolescents, as well as in adults at reproductive age. Currently, 40.3% of men and 39.7% of women 20–39 years of age in the United States are classified as obese, leading to a substantial rise in pa...

J. D. Do Carmo, John E. Hall, Zhen Wang et al. · Current Hypertension Reports · 0 citations

Open access Sep 2026

Impaired mitochondrial proteostasis underlies cardiomyocyte bioenergetic dysfunction in a murine 3-hit model of heart failure with preserved ejection fraction.

Heart failure with preserved ejection fraction (HFpEF) predominantly affects older individuals with multiple comorbidities. Although mitochondrial dysfunction appears to be a major contributor to diastolic dysfunction, the mechanisms underlying it during HFpEF remain unclear. We used a clinically relevant two-hit HFpEF...

Xuan Li, Yi-Ling Fu, J. D. Do Carmo et al. · American Journal of Physiolo... · 0 citations