A. D. Farista

Lynch Syndrome in a Young Male Patient: A Rare Case Report with Diagnostic Considerations

Introduction: Lynch syndrome, (LS), or hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal dominant inherited cancer syndrome primarily caused by germline mutations in DNA mismatch repair (MMR) genes, particularly MLH1 and MSH2. These mutations cause microsatellite instability (MSI), a hallmark of LS-ass...