Up-Front Immune Checkpoint Inhibitors in Patients with Multiple Synchronous Primary Tumors, Including dMMR/MSI-H Gastrointestinal Malignancies: A Case Series and Review of the Literature
Simple Summary Patients with a concurrent diagnosis of multiple primary tumors present a particularly complex challenge in terms of determining the appropriate treatment, as these patients are generally excluded from clinical trials—especially if they have other comorbidities—due in part to the risks associated with su...