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Author

A. De Simone

1 paper indexed here

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Review Jul 2026

Bioisosteric Replacement of Carboxylic Acids in PPAR Agonists: A Mini Review.

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate metabolic homeostasis and represent important therapeutic targets for conditions such as type 2 diabetes, dyslipidemia, and cardiovascular disease. While classical modulators often rely on carboxylic acid moieties to anchor receptor...

Adriana Coricello, A. De Simone, Giovanni Bottegoni · 0 citations

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