Author

A. Digklia

2 papers indexed here

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Review Open access Sep 2026

Systemic treatment paradigms for unresectable and advanced hepatocellular carcinoma in Europe

Summary The management of unresectable and advanced hepatocellular carcinoma (HCC) has been transformed by the introduction of immune checkpoint inhibitor-based combinations, which have improved response and survival and expanded first-line treatment options. The availability of multiple effective regimens has introduc...

D. Pinato, E. Alimenti, Pasquale Lombardi et al. · The Lancet Regional Health -... · 1 citation

Open access Sep 2026

Familial Pancreatic Cancer Associated with a Shared BRIP1 Variant: Implications for Homologous Recombination Deficiency and Targeted Therapy

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a subset occurring in the context of hereditary cancer predisposition. BRIP1 is involved in homologous recombination repair, and pathogenic germline variants are established risk factors for ovarian cancer. However, its role in pa...

Nils Degrauwe, Giovanni Dei Tos, M. Trimech et al. · Genes · 0 citations