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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

A. Dosch

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Sep 2026

Abstract A006: A p38α MAPK-TCF21 axis regulates pancreatic stellate cell activation and stromal reprogramming in pancreatic cancer

Pancreatic stellate cells (PSCs) are a principal source of cancer-associated fibroblasts (CAF) in pancreatic ductal adenocarcinoma (PDAC), yet the mechanisms that convert tumor-derived inflammatory cues into a persistent, CAF-like state remain poorly defined. We previously identified tumor cell-intrinsic p38α MAP...

Sayan Chakraborty, Camille Acevedo, Samara P. Singh et al. · 0 citations

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