Author

A. Drakaki

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Review Open access Aug 2026

Multi-level transcriptional control of specific macrophage responses.

Macrophages can adopt diverse functional states in response to environmental cues, a process that is fundamentally controlled at the level of transcriptional regulation. In this review, we outline a hierarchical framework of transcription factor activity that underpins macrophage identity and activation. Firstly, linea...

A. Drakaki, Josje M. A. Huisman, Marten A. Hoeksema · EMBO Journal · 0 citations

Open access Jul 2026

Allogeneic CD70-Targeted Chimeric Antigen Receptor T-Cell Therapy for Advanced Renal Cell Carcinoma: Results From the Phase I TRAVERSE Trial

The TRAVERSE trial demonstrates proof of concept for the role of allogeneic CAR T-cell therapy in solid tumors and had manageable safety and encouraging antitumor activity in CD70-positive ccRCC.

S. Srour, J. Chahoud, A. Drakaki et al. · Journal of Clinical Oncology · 0 citations