Author

A. Droit

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Open access Sep 2026

Mapping virulence-associated protein interaction networks reveals regulators of thermotolerance in Cryptococcus neoformans

Protein-protein interactions (PPIs) influence critical biological processes in pathogenic microorganisms, such as the human fungal pathogen, Cryptococcus neoformans. Fungal thermotolerance and stress response pathways are key virulence determinants that directly impact pathogen adaptation and survival and the infection...

Mayara Barbara da Silva, Mariana Cavalcante Almeida Sa, Florence Roux-Dalvai et al. · bioRxiv · 0 citations

Open access Sep 2026

Rapid Species-Level Classification of Urinary Pathogens from Raw LC-MS/MS Signals Using Machine Learning

These results show that raw LC-MS/MS spectra contain sufficient biological information for direct microbial diagnosis, establishing an analytical framework for clinical mass spectrometry and positions raw signal inference as a promising direction for next-generation diagnostic mass spectrometry.

Simon J. Pelletier, Antoine Lacombe-Rastoll, Florence Roux-Dalvai et al. · Analytical Chemistry · 0 citations

Open access Aug 2026

An in-depth update on the benchmarks for 16S amplicon sequencing

This study conducted a comprehensive benchmark of the main bioinformatic tools and databases and demonstrated that even certain dominant genera remain difficult to detect, and that the quantification of all genera can be substantially over- or under-estimated, even when using optimal combinations of tools and reference...

Louis-Maël Guéguen, Alban Mathieu, Olivier Périn et al. · bioRxiv · 0 citations