Review
Open access
Sep 2026
Breaking Biological Barriers: Engineering Nanocarriers for Efficient Drug and Gene Delivery through Nano-Bio Interfaces and Biophysical Design
A persistent challenge in nanomedicine is achieving functional delivery of therapeutic molecules across physiological barriers. Organs impose distinct transport constraints, including the blood–brain barrier, renal filtration, hepatic sequestration, and pulmonary clearance. Although substantial effort has focused on en...
Zicheng Deng, A. Dunn, Daniel Q. Sun et al.
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