Quinoline Scaffold in Drug Discovery: Synthetic Strategies, Therapeutic Applications, and Emerging Drug Candidates
Quinoline is a bicyclic aromatic heterocycle composed of a fused benzene and pyridine ring, and it has held an important place in medicinal chemistry for nearly two centuries. F. Runge first isolated it from coal tar in 1834, and it was later found to form the structural core of well-known natural products such as quin...