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Alysha G. Elliott

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Open access Aug 2026

Mapping the resistance landscape: A large-scale study of polymyxin-resistant pathogens circulating in low-and middle-income countries

The increasing prevalence of antimicrobial resistance is a major public health challenge, particularly in low- and middle-income countries (LMICs). Polymyxins are last-resort antibiotics used for treating highly drug-resistant infections, however, the rise of polymyxin-resistant bacterial strains is further reducing tr...

T. Duarte, Holly Floyd, V. Thamlikitkul et al. · 0 citations
Open access Aug 2026

Cationic metal-binding coumarin amphiphiles as membrane-active antimicrobial agents.

The results suggest that incorporating metal-binding headgroups into amphiphilic scaffolds may engage a distinct mode of action compared to traditional small-molecule AMP mimetics, resulting in increased antimicrobial potency and selectivity over mammalian membranes.

Samuel O. Nitschke, Anteneh Amsalu, Muhammed Awad et al. · 0 citations

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