Design and In Silico Evaluation of a Cry1Ac/XptC Hybrid Protein Targeting the APN Receptor in Manduca sexta
Background: The widespread use of Bacillus thuringiensis (Bt) Cry toxins has led to the evolution of resistance in target insect pests, posing a significant threat to sustainable agriculture. Manduca sexta, a major pest of Solanaceae crops, is developing resistance to conventional Cry1Ac toxins, necessitating the devel...