Open access
Sep 2026
From wild to domestic: Single-cell transcriptomic perspectives on hippocampal regulation and evolution.
How domestication shapes brain evolution remains an open question. In this study, we integrated single-nucleus RNA sequencing (snRNA-seq), population genomics, and machine learning to investigate the hippocampal evolution under domestication. Across-species comparisons revealed that hippocampal cell type profiles are l...
Lirong Hu, Yun-Mei Wang, Jing-Yi Xie et al.
· Proceedings of the National... · 0 citations