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A. F. van Velzen

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Open access Oct 2026

Predicting HPV/p16 Status and Molecular Subtypes from Histopathology Slides using Deep Learning in Vulvar Squamous Cell Carcinoma

Vulvar squamous cell carcinoma (VSCC) comprises three prognostically distinct molecular subtypes: human papillomavirus (HPV)-associated, HPV-independent/p53-wildtype, and HPV-independent/p53-abnormal. Classification requires p16/p53 immunohistochemistry, which consumes tissue and is often incomplete in retrospective co...

N. J. van den Berg, W. L. Van der Kolk, K. Landsbergen et al. · 0 citations

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