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Author

A. Gaspardone

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Open access Aug 2026

Left atrial appendage closure versus medical therapy in atrial fibrillation: An updated meta-analysis of randomized trials on the trade-off between stroke prevention and bleeding.

LAAC provides thromboembolic protection comparable to medical therapy while reducing non-procedural bleeding, and its role as an alternative strategy in selected patients at increased bleeding risk is supported.

G. Di Pietro, Riccardo Improta, E. Bruno et al. · 0 citations
Review Open access Jul 2026

Lipoprotein(a) in Coronary Artery Disease and Aortic Stenosis: Pathophysiology, Clinical Impact, Interventional Implications and Emerging Targeted Therapies

Overall, Lp(a) should be regarded as both a meaningful biomarker and a promising therapeutic target, although ongoing outcome trials are needed to determine whether selective Lp(a) lowering translates into clinical benefit across interventional cardiovascular settings.

F. M. Animati, Simone Proietti, Francesco Auletta et al. · 0 citations

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