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Review Open access Oct 2026

Human Antibody Responses to Group A Streptococcus Infection: A Systematic Review.

OBJECTIVES Group A Streptococcus (GAS) is a leading global cause of infectious disease morbidity and mortality. A major barrier to GAS vaccine development is our incomplete understanding of human immunity. We undertook, to our knowledge, the first systematic review describing human antibody responses following GAS infe...

Rachael Barr, Hannah Frost, Yara-Natalie Abo et al. · 0 citations
Review Open access Sep 2026

T cells in Group A Streptococcus infection: protection or pathology?

Streptococcus pyogenes (Group A Streptococcus; GAS) is a World Health Organization (WHO) priority pathogen for vaccine development. GAS vaccine development and trials have been impeded by a poor understanding of GAS immunity, and to date no correlate of protection has been identified. The predominant focus of efforts h...

L. Mathew, Mohammad Ali, H. Townsley et al. · 0 citations

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