Open access
Oct 2026
Endothelial p22phox-dependent NADPH oxidases govern regional myocardial vulnerability in Takotsubo syndrome
Takotsubo syndrome (TTS) is an acute heart failure syndrome characterized by transient, regionally confined left ventricular (LV) systolic dysfunction triggered by catecholamine excess. Beyond dysregulated β-adrenergic signaling, endothelial oxidative stress and inflammation contribute to TTS pathophysiology. cAM...
S. Kerth, A. Petry, T. Tatarcheh et al.
· European Heart Journal · 0 citations