Open access
Aug 2026
SYCP3 enhances prostate cancer metastasis and modulates the DNA damage response pathway
Biological validation analyses showed that SYCP3 depletion significantly reduced the invasive and migratory abilities of DU145 cells and increased their adhesion capacity, suggesting a role for SYCP3 in DNA damage response and genomic instability in PCa metastasis.
M. Rodrigo-Faus, I. Del Monte-Garcia, Marina Hermosilla-Trespaderne et al.
· Scientific Reports · 0 citations