Diminished Pro-Inflammatory Characteristics in Murine Bone Marrow Derived Macrophages with Impaired Thyroid Hormone Receptor Alpha 1 Signaling
Background: Macrophages are versatile phagocytes of the innate immune system with functions ranging from pro-inflammatory to immunomodulatory. Macrophages are receptive to signals from thyroid hormones (THs). Here, we studied the role of the TH receptor (TR)α1 in macrophage function. Methods: Using wild type (WT) and t...