Open access
Aug 2026
Rational design, synthesis, and antimicrobial evaluation of novel 1,2,3-triazole hybrids: structure–activity relationships, molecular docking, and DFT studies
The results suggest that the 2,4-dichlorophenyl–1,2,3-triazole scaffold represents a promising starting point for further optimization, with antimicrobial activity governed by a balance between electronic properties and physicochemical factors influencing membrane permeability.
Mohammed Sallam, A. Hassan, A. Y. Alzahrani et al.
· Scientific Reports · 0 citations