Review
Open access
Sep 2026
Metabolic modulators as gatekeepers of immunotherapy response in colorectal cancer
Colorectal cancer (CRC) continues to pose a significant global health concern, largely driven by metabolic reprogramming mechanisms that facilitate tumor progression and enable immune evasion within the tumor microenvironment (TME). This review highlights the pivotal functions of dysregulated metabolic pathways, such...
Alireza Najafi, Ali Rahimi, Zeinab Baghernejadian et al.
· Cancer Cell International · 0 citations